Plasmodium falciparum ATP4 (PfATP4) is a Na + efflux pump and represents an important target for antimalarial drugs with nanomolar potency. However, the structure of PfATP4 is unknown, prompting the development of new methodologies to ...Among new antimalarials discovered over the past decade are multiple chemical scaffolds that target Plasmodium falciparum P-type …

Commentaries call attention to articles of particular note.. Inaugural Articles may be submitted by newly elected NAS members as a way to introduce themselves to the readers of PNAS and may present new ideas or hypotheses or describe the historical development of the member’s field.View the Inaugural Articles collection.. Front Matter is a magazine section that tells the …

Soils are estimated to contribute up to 25% of the potential of natural climate solutions for climate change mitigation, particularly in agricultural croplands ().Aside from the mitigation of climate change, increases in SOC in agricultural ecosystems also enhance soil quality and food security ().The sequestration of SOC in agricultural soil is a hot topic in major policy initiatives and ...

Dec 17, 2024 · Browse the most-recent publications from PNAS, publishing daily across the physical, social, and biological sciences.

Liquid–liquid phase separation (LLPS) of proteins and nucleic acids (1–4) is a versatile intracellular process, which leads to the formation of biomolecular condensates (BMCs).The occurrence of LLPS was shown to be a widely spread phenomenon in biology ().The detailed LLPS process and the thus-forming BMCs were first revealed by Brangwynne et al. by …

Useful features. PNAS content collections and journal features offer fresh perspectives on science at a general level, including coverage of trending topics, expert opinions, explanations of core scientific concepts, and intersection of science and culture— enhancing understanding across disciplines.. Registered users gain access to additional tools, such as email alerts, saved …

PNAS provides several article-level metrics for all articles. Click on the “Info & Metrics” tab of any PNAS article to see its Altmetric score, citation counts, and usage data, including downloads of the abstract, full text, and PDF. PNAS encourages responsible authorship practices and provides ...

Nov 8, 2024 · Drylands are vulnerable to both natural and anthropogenic perturbations (13, 18, 19).Land degradation over the past decades or centuries, resulting mainly from intensified human activities (), has led to widespread wind erosion and frequent dust storms in drylands across the world (21–23).Given that 44% of organic matter in the top 30 cm of soil worldwide is stored in …

Natural communities, from a microbiome to a forest, have a profound impact on humanity, influencing individual well-being and the sustainable development of societies (1, 2).Within these ecosystems, the interplay among millions of organisms from numerous species both within and between trophic levels (3, 4)—such as fighting for territories (), predation (6–8), competing for …

A PDF list of Editorial Board members and staff members is posted on the current issue Table of Contents; click on the [Masthead (PDF)] link in the upper right corner.