Here, we review various aspects of the adipocyte extracellular matrix (ECM) including its components, development, regulation, and relation to obesity. Adipose tissue is histologically …

Nov 3, 2023 · Adipose tissue is distributed within two compartments of the human body: Visceral fat, which surrounds the internal organs, such as eyeballs (periorbital fat) or kidneys (perirenal …

The extracellular matrix in adipose tissue is not only a simple morphological structure but provides a biochemical and biomechanical context in adipocyte dynamic behavior, modulating …

A key structural and functional component of adipose tissue is made up of extracellular matrix (ECM) molecules, including collagen and proteoglycans such as versican and biglycan, among …

Jan 14, 2022 · To address this clinical need, we developed an “off-the-shelf” adipose extracellular matrix (ECM) biomaterial from allograft human tissue (Acellular Adipose Tissue, AAT). We …

Jun 4, 2024 · Adipose tissue is composed of adipocytes or fat cells, which store energy in the form of fat molecules called triglycerides. These cells are embedded in a matrix of connective …

Feb 6, 2024 · ATAT utilizes local and image-level differentials in pixel intensity to independently threshold image background, distinguishing adipocyte-free tissue without user input.

Context: Insulin resistance is associated with inflammation, fibrosis, and hypoxia in adipose tissue. Objective: This study was intended to better characterize the extracellular matrix (ECM) …

Adipose tissue (AT) expansion in obesity is characterized by cellular growth and continuous extracellular matrix (ECM) remodeling with increased fibrillar collagen deposition. It is …

Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy …