Adipose tissue inflammation is initiated and sustained over time by dysfunctional adipocytes that secrete inflammatory adipokines and by infiltration of bone marrow-derived immune cells that …

Adipose tissue inflammation in obesity differs from typical inflammatory responses employed in host defense in that it is chronic, sterile, low grade, and affects the metabolic control of nutrient …

Adipose tissue produces and releases a variety of pro-inflammatory and anti-inflammatory factors, including the adipokines leptin, adiponectin, and resistin, as well as cytokines and …

Aug 11, 2017 · We examine the connection between adipose tissue inflammation and the development of insulin resistance and catecholamine resistance and discuss the ensuing state …

Small adipocytes in lean individuals promote metabolic homeostasis; the enlarged adipocytes of obese individuals recruit macrophages and promote inflammation and the release of a range …

Nov 7, 2024 · Adipose tissue releases adipokines, which are mediators of metabolic inflammation that control metabolic and immune responses in and beyond the tissue they are released from.

Jan 21, 2011 · Highly inflamed, metabolically dysfunctional adipose tissue is characterized by macrophage infiltration, capillary rarefaction and adipocyte necrosis. Adipokines and adipose...

Jan 15, 2024 · Obesity is a current global challenge affecting all ages and is characterized by the up-regulated secretion of bioactive factors/pathways which result in adipose tissue …

Recent studies have shown that obesity induces chronic local inflammation in adipose tissue, and that cells of the innate immune system, particularly macrophages, are crucially involved in …

Mar 1, 2021 · Adipose tissue inflammation is initiated and sustained over time by dysfunctional adipocytes that secrete inflammatory adipokines and by infiltration of bone marrow-derived …