Too Old to Operate3h
KEYNOTE-522 Shows Prognostic Value of TMB & Biomarkers in Triple-Negative Breast Cancer
TMB and various biomarkers were positively associated with improved pCR and EFS in high-risk, early-stage TNBC, regardless of ...
Too Old to Operate3h
Deferring CDK4/6 Inhibitor Treatment in HR-Positive/HER2-Negative Advanced BC May Not Impact HRQOL
The phase 3 SONIA trial showed deferring CDK4/6 inhibitor treatment may not compromise HRQOL in patients with HR-positive/HER2-negative advanced breast cancer.
Too Old to Operate4h
Olaparib Shows Long-Term Benefit in High-Risk BRCA1/2-Mutated Breast Cancer
Olaparib improved invasive disease-free survival, distant disease-free survival, and overall survival in high-risk ...
Too Old to Operate4h
Neoadjuvant SHR-A1811 Shows Promise in Fighting HER2-Positive Breast Cancer
Neoadjuvant SHR-A1811 showed similar pathologic complete response rates to the standard 4-drug regimen in patients with ...
Too Old to Operate5h
Margetuximab Does Not Improve pCR Rate in HER2-Positive Early Breast Cancer
The MARGOT/TBCRC052 trial didn't show improvement in pathologic complete response rates with margetuximab for early-stage HER2-positive breast cancer.
Too Old to Operate5h
Improved TFF & PFS Seen With Palbociclib Plus ET in Real-World PADMA Study
The phase 4 PADMA study showed meaningful improvements in TFF and PFS in patients with high-risk HR-positive/HER2-negative metastatic breast cancer.
Too Old to Operate6h
Inavolisib FDA-Approved for Triplet Combination Use for Metastatic Breast Cancer
The FDA approved inavolisib for triplet combination use for treatment of PIK3CA-mutated locally advanced or metastatic ...
Too Old to Operate6h
Success With Adjuvant Ribociclib Leads to FDA Approval in Early Breast Cancer
The FDA approved ribociclib, a CDK4/6 inhibitor, providing an additional treatment option for patients with early breast cancer at high risk for recurrence.
Too Old to Operate6h
Ultrasound Prognostic Value for Predicting COVID-19 Hospitalization and ICU Admission
The following is a summary of “Clinical and ultrasound characteristics in patients with sars-cov-2 pneumonia, associated with ...
Too Old to Operate7h
Increased Biosignal Entropy Associated with Poor TBI Outcomes
The following is a summary of “Dynamic assessment of signal entropy for prognostication and secondary brain insult detection ...
Too Old to Operate7h
Characterization of Immune Cell Dynamics in Psoriasis Lesions
The following is a summary of “FC02 Immune cell signatures and T-cell receptor profiling reveal pathogenetic mechanisms in psoriasis,” published in the December 2024 issue of Dermatology by Deng et al ...
Too Old to Operate7h
Bayesian Analysis of Protein Delivery and Mortality in Critical Care
The following is a summary of “Higher Versus Lower Protein Delivery in Critically Ill Patients: A Systematic Review and ...