Good luck trying to predict what will happen during the 2025 NCAA Tournament. There are several talented teams capable of making deep runs through this year's bracket. Duke (ACC), Houston (Big 12), Michigan State (Big Ten) and St.

Sixteen games across the country Thursday opened up the first round of the 2025 NCAA Tournament and probably to some extent busted at least part of your March Madness bracket in the process. Maybe you picked High Point to take down Purdue or thought No.

The NCAA will also stream games via its March Madness Live option. The top betting favorites as the tournament begins: Florida and Duke are listed as co-favorites (+325), according to BetMGM Sportsbook. Auburn (+425) and Houston (+600) are next.