Esaxerenone exerts its therapeutic effects by selectively binding to and inhibiting the mineralocorticoid receptor (MR). The MR is a nuclear receptor that, when activated by aldosterone, triggers a ...

Chronic kidney disease (CKD) has diverse etiologies and complex pathogenesis, and is prone to recurrent episodes and prolonged illness. In recent years, the prevalence of CKD has been increasing year ...

Lipid abnormalities are a common complication in diabetic kidney disease (DKD), contributing to disease progression and ...

Keywords Diabetes Mellitus, Retinopathy, Neuropathy, Nephropathy, Cardiovascular Disease Share and Cite: Mohammed, S. , ...

The global burden of diabetic nephropathy increased from 1990 to 2021, and is projected to continue increasing to 2050.

AAR Hospital is expanding its dialysis services in response to increasing demand, a trend reflecting the growing economic ...

The survival rate is extremely low due to severe complications like hypoglycaemia and diabetic ketoacidosis (DKA). Early ...

Department of Medicine, University of Arizona College of Medicine, Tucson, USA. Background: Diabetic nephropathy is the most common cause of chronic kidney disease and the number afflicted patients ...

Vertex Pharmaceuticals Incorporated today announced several updates on the Company's type 1 diabetes (T1D) portfolio. VX-264 Update Vertex has completed enrollment and dosing in Parts A and B of the ...