Background:In obesity and type 2 diabetes mellitus (T2D), adipose tissue expansion (because of larger adipocytes) results in reduced microvascular density which is thought to lead to adipocyte hypoxia ...

Research carried out on mice has revealed how a hormone released by the intestine acts on the brain and helps regulate the ...

In the lean, healthy state, adipose tissue (AT) has critical roles in maintaining organismal homeostasis. Paramount among the various roles of AT is the regulation of whole body metabolism. While ...

Alterations in visceral adipose tissue (VAT) are closely linked to cardiometabolic abnormalities. The aim of this work is to define a metabolic signature in VAT of insulin resistance (IR) dependent on ...

But as the body ages, the activity of brown adipose tissue decreases. This inactivation of brown adipose tissue—also typical of obese people—remains poorly studied in the scientific literature.

Brown adipose tissue has a protective function against these prevalent diseases, as it burns calories and can produce body heat from fat. But as the body ages, the activity of brown adipose tissue ...

Improvement of dietary protein content is of high interest for increasing the success of dietary intervention for management of metabolic diseases such as obesity/type-2 diabetes. The prevalence of ...

Stromal vascular fraction cells isolation from adipose tissue. The eAT from each mouse was collected with a mixture of DMEM (Cat. no. 10–027-CV, Corning, NY) and RPMI media (Cat. no. 10–041-CV, ...