Medically reviewed by Nicholas R. Metrus, MD Huntington’s disease is a hereditary disorder that causes a progressive decline ...

Medically reviewed by Nicholas R. Metrus, MD Huntington’s disease is a hereditary degenerative neurological disease that ...

Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into ...

UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

Huntington’s disease was long thought to be caused by the slow buildup of a toxic protein, but new research has revealed that it’s actually driven by the expansion of a gene that, at a certain ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

The data were analyzed for linkage to the Huntington's disease gene using the program LIPED with a correction for the late age of onset. Because of the high frequency of the Huntington's disease ...

ElevateBio is seeking out partnerships for its lead gene therapy after the construct reduced the levels of a toxic protein in mice with Huntington’s disease by more than 80%. The therapy had no ...

Huntington's disease (HD) is a hereditary neurodegenerative disorder ... of the caudate nucleus on brain imaging. Today, DNA testing can reliably diagnose HD and differentiate the disease from other ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...