In human cirrhotic liver, gene (>30-fold), protein expression (97-fold), and activity of ACE2 (2.4 fold) were increased compared with controls (all p<0.01). In healthy livers, ACE2 was confined to ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an ...

Fatty liver disease, caused by the accumulation of fat in the liver, is estimated to affect one in four people worldwide. If ...

Liver diseases are increasing globally, marked by conditions like NAFLD, hepatitis, and cirrhosis, leading to a surge in ...

Fatty liver disease, caused by the accumulation of fat in the liver, is estimated to affect one in four people worldwide. If ...

This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression.

Alcohol-associated liver disease mortality doubled from 1999 to 2022, with pronounced increases among women, younger adults, and American Indian and Alaska Native populations, according to study ...

Waist-to-height ratio (WHtR) outperforms body mass index (BMI) in detecting the risk for liver disease, according to a study published in the July issue of the Journal of the Endocrine Society. Andrew ...

A liver that is damaged in women with cirrhosis may not metabolise and clear oestrogen effectively, resulting in too much of the hormone circulating in the body. This can manifest as: 3.

Background ‘Acute-on-chronic liver failure’ (ACLF) is characterised in a more advanced stage by liver failure associated with multiple other end-organ failure. The global clinical characteristics of ...

Addressing the mechanistic underpinnings of albumin’s effects, a translational study from Leiden University Medical Center, the Netherlands, explored the impact of human albumin on endothelial cell ...