Frontiers3d
Pre-Weaning Exposure to Maternal High-Fat Diet Is a Critical Developmental Window for Programming the Metabolic System of Offspring in Mice
The lower UCP1 levels and HSL phosphorylation in LH offspring further suggested that brown adipose tissue (BAT) thermogenic function ... HFD causes adverse consequences and its specific mechanisms in ...
Adipose tissue atlas identifies metabolically healthy vs unhealthy obesity
Although obese individuals are at greater risk of diabetes, high blood pressure or high cholesterol, not all obese people ...
Science Daily1d
How hungry fat cells could someday starve cancer to death
Liposuction and plastic surgery aren't often mentioned in the same breath as cancer. But they are the inspiration for a new approach to treating cancer that uses engineered fat cells to deprive tumors ...
Medscape5d
Reversal of Obesity by Targeted Ablation of Adipose Tissue
The uptake of CKGGRAKDC-FITC by the endothelium of white fat tissue suggests that the motif is preferentially internalized by a receptor in the adipose vasculature that may serve for targeted ...
Frontiers3d
Adipose tissue macrophages as potential targets for obesity and metabolic diseases
Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose tissue dysfunction and contributing to obesity-induced inflammation and metabolic disorders. In this review, ...
gut.bmj2d
Single-cell omics in inflammatory bowel disease: recent insights and future clinical applications
For decades, the study of the mechanisms underlying these diseases has relied on technologies such as immunophenotyping, or bulk transcriptional analysis of tissue or blood. However, bulk approaches, ...
The EMBO Journal3d
Cytosolic DNA sensors in neurodegenerative diseases: from physiological defenders to pathological culprits
Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...