Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose tissue dysfunction and contributing to obesity-induced inflammation and metabolic disorders. In this review, ...

Accumulating evidence reveals that adipose tissue is an immunologically active organ that exerts multiple impacts on the regulation of systemic energy metabolism. Adipose tissue immunity is modulated ...

Survival during fasting requires release of adipose tissue lipid stores and is thought ... Here the authors develop a Macrophage Drug Conjugate (MDC) platform by loading ferritin-drug complexes ...

Although obese individuals are at greater risk of diabetes, high blood pressure or high cholesterol, not all obese people ...

Time-restricted eating may not add additional benefit in visceral adipose tissue reduction over the Mediterranean diet for people with overweight or obesity.

Body weight and body mass index alone are not enough to predict whether someone will develop a metabolic disease. A new atlas of cells in fat tissue could help to explain why some overweight people ...

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC. New research from the ...

Increased intermuscular fat is associated with coronary microvascular dysfunction and adverse cardiovascular outcomes.

Researchers have been trying for decades to stop the cells that damage the lung in people with pulmonary fibrosis. Now a team ...

Recent advances in single-cell and single-nucleus transcriptomics have provided new insights into the complexity of fat ...

For decades, the study of the mechanisms underlying these diseases has relied on technologies such as immunophenotyping, or bulk transcriptional analysis of tissue or blood ... included inflammatory ...