Tribune News NetworkDohaSidra Medicine, a member of Qatar Foundation, has contributed to a major international research study published in Nature Metabolism, titled ‘Towards a consensus atlas of human ...

Obesity plays a crucial role in how severely blood vessels are damaged—and this depends on where excessive fat accumulates in ...

The researchers also noted that every 1% increase in fatty muscle fraction — defined as total intermuscular adipose tissue divided by the summation of skeletal muscle and intermuscular adipose ...

This adipose tissue dysfunction has shown to be associated with a higher risk of CVD and CKD in obesity and metabolic syndrome. However, little is known about the mechanisms underlying this potential ...

Paired abdominal and femoral subcutaneous adipose tissue (AT) biopsies from 18 postmenopausal women (Body mass index (BMI): 21.2-40.6 kg/m², age: 50-62 years) were analyzed for p53 messenger RNA ...

Among the biological mechanisms that link increased body fat mass to cardio-metabolic diseases, AT dysfunction is a major determinant of the individual obesity-associated risk (14, 15). The concept of ...

When the team deleted RalA in the white adipocytes of mice fed a high-fat diet, rodents were both protected from mitochondrial fragmentation and obesity, even when they ate the same high-fat diet as ...

Obesity, which affects more than 40% of adults in the United States, occurs when the body accumulates too much fat, which is primarily stored in adipose tissue.

“Adipose tissue macrophage (ATM) infiltration is associated with adipose tissue dysfunction and insulin resistance in mice and humans,” wrote the researchers.

He goes on to explain that in people with adipose tissue dysfunction, this can lead to damaged tissue, fibrosis, secretion of proinflammatory and adipogenic molecules that subsequently contribute ...