Singlera Genomics presented results showing a refined approach to detect drug-induced testicular toxicity using Singlera’s ...

When an organ is injured, our body initiates a healing process. If the injury is repeated or chronic, it can lead to an ...

F528, a novel anti-inflammation agent with the potential to modify the progression of chronic obstructive pulmonary disease ("COPD”), is undergoing preclinical studies as a potential first-line ...

Mice were anaesthetized with methoxyflurane (Metafane; Mallinckrodt Veterinary) and rats ... period of liver regeneration for these species. In some experiments an osmotic minipump (model 2001 ...

“ReShape’s Diabetes Neuromodulation technology regulates blood glucose by selectively modulating vagal block and stimulation to the liver and pancreas. Studies have shown improved glycemic control in ...

Figure 3: a–c, Liver sections of rats after DMN administration. Sprague–Dawley rats 4–5 weeks old and 120–130 g in body weight were used. To produce liver cirrhosis, 1% DMN dissolved in ...

Non-Commercial (NC): Only non-commercial uses of the work are permitted. Drug-induced liver injury (DILI) is a major cause of drug development failures and postmarket drug withdrawals, posing ...

Shilajit, a traditional herbal medicine available in supplements, may improve health issues ranging from Alzheimer’s disease and high cholesterol to weak, brittle bones (osteoporosis). Some people ...

To build the hepatocyte steatosis model, the cells were exposed to sodium palmitate ... Liver injury manifested by hepatic cell apoptosis was also observed in ZDF rats and PA treated liver cells.

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

Correspondence to Dr Pere Ginès, Liver Unit, Hospital Clinic of Barcelona, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona 08036, Spain; ...