Collagen, which is considered as a key component for healthy skin may be worsening your type 2 diabetes. Read what the new ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

Two recent studies from Dr. Sita Kugel’s lab at Fred Hutch Cancer Center identify a key biological signature that not only ...

The ability to characterize chemical heterogeneity in biological structures is essential to understanding cellular-level function in both healthy and diseased states, but these variations remain ...

Toward a Fully Automated Artificial Pancreas System Using a Bioinspired Reinforcement Learning Design: In Silico Validation Abstract: Objective: The automation of insulin treatment is the most ...

The ability to assay the molecular composition of biological systems with single-cell resolution has revolutionized our understanding of tissue heterogeneity and function. Recent advances in ...

It is currently difficult for pathologists to diagnose pancreatic cancer (PC) using biopsy specimens because samples may have been from an incorrect site or contain an insufficient amount of tissue.

We evaluated pancreatic enzyme secretory response to secretagogues (cAMP- and Ca 2+ -mediating) involved in exocytosis and in chloride channel activation in an exon 10 knockout cystic fibrosis (CF ...

Objective Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease and cytotoxic chemotherapy is the standard of care treatment for patients with advanced disease. Here, we investigate ...