We find that reducing SirT1 expression in lean animals is sufficient to cause adipose tissue NF-κB activation, tissue and plasma cytokine elevations, and macrophage infiltration similar to that ...

Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose tissue dysfunction and contributing to obesity-induced inflammation and metabolic disorders. In this review, ...

Pioglitazone was associated with a lower risk of developing skin ulcers in patients with Werner disease in a Japanese study, ...

Ozempic and Wegovy do the same thing as GLP-1 would normally do for you — but to enable them to treat diabetes and obesity, ...

Accumulating evidence reveals that adipose tissue is an immunologically active organ that exerts multiple impacts on the regulation of systemic energy metabolism. Adipose tissue immunity is modulated ...

Researchers at the, Riverside, backed by a substantial NIH grant, are pioneering a study on the unique immune responses to ...

According to the Centers for Disease Control and Prevention, more than two in five American adults have obesity, a common and costly chronic disease. Linked to chronic conditions like type 2 diabetes ...

Survival during fasting requires release of adipose tissue lipid stores and is thought ... Here the authors develop a Macrophage Drug Conjugate (MDC) platform by loading ferritin-drug complexes ...

This should be valuable for the growing number of investigators in the field of adipose tissue biology that are utilizing snRNA ... the majority of the highlighted cell types including APCs, ...