Infielder Luis Guillorme began a minor-league rehab assignment Wednesday with Triple-A Sugar Land in his recovery from a right hamstring strain. Guillorme was placed on the 10-day injured list July 2, after playing in 12 games with the Astros as a utility infielder.

The first Diamondbacks trade domino has fallen, as first baseman Josh Naylor is heading to the Seattle Mariners.

The Arizona Diamondbacks were swept in a three game series by the Houston Astros this week, dropping their record to 50-53. That leaves them still 5.5 games out

The Astros close out a six-game road trip with a chance to extend their three-game winning streak as Bandon Walter pitches against Arizona.

The Arizona Diamondbacks turn to Brandon Pfaadt, who, with his long-term contract, wouldn't seem to be a player they'd trade.

Preview the July 23 matchup between the Houston Astros and Arizona Diamondbacks with odds over/under, game spread, betting lines and more.

Christian Walker singled home the go-ahead run in the ninth inning and the Houston Astros beat the Arizona Diamondbacks 4-3 on Wednesday to complete a three-game sweep. Zack Short and Taylor Trammell started the ninth with bunt singles against Kevin Ginkel (1-4).

The Arizona Diamondbacks gave the front office a perfect snapshot of 2025 in getting swept by the Houston Astros, finishing with an ugly, 4-3 loss.

The Houston Astros and Arizona Diamondbacks meet Wednesday at Chase Field for the final game of their 3-game series.

BOTTOM LINE: The Houston Astros seek to build upon a three-game win streak with a victory over the Arizona Diamondbacks. Arizona has a 50-52 record overall and a 26-27 record at home. The Diamondbacks have the fifth-ranked team batting average in the NL at .253.

Arizona Diamondbacks' Eduardo Rodriguez on holding the Houston Astros without a run for more than six innings on July 22, 2025.