played by Margaret Qualley. Demi with long dark hair looks at her reflection in a tiled bathroom mirror, wearing a dark top, appearing contemplative Margaret in strapless dress smiles during a TV ...

After she takes a black-market drug, she creates a younger, better version of herself (Qualley) — with dire consequences. Both Moore, 62, and Qualley underwent shocking transformations for the film.

But I mean that in a good way," Qualley tells IndieWire. Even Margaret Qualley can’t get ... She continued, “I ran to the bathroom and had to collect myself and come back.

“So, you know the character that has all that acne? That was just my acne from the prosthetics,” Qualley, who plays characters Vivian, Martha, Ruth and Rebecca in the Yorgos Lanthimos-directed ...

For The Substance, Moore plays an aging actress in the film who obtains a black market drug to create a younger version of herself (Qualley) in a bid to remain relevant -- with disastrous ...

Margaret Qualley’s skin went through a lot on the set of The Substance. In a Jan. 13 episode of Josh Horowitz’s Happy Sad Confused podcast, the Golden Globe nominee, 30, got real about the ...

Margaret Qualley says filming “The Substance” left ... Sparkle turns to the black market for an illicit drug that creates a younger version of herself with grotesque side effects.

Known for her impressive performances in films like "Maid" and "Once Upon a Time in Hollywood," Margaret Qualley showcased her talent yet again in "The Substance." Starring alongside Demi Moore ...

Hollywood star Margaret Qualley ... of a black market drug known as the Substance, which promises to deliver her a younger version of herself named Sue, played by Qualley, with certain caveats.