Study Finds Surprising Way That Genetic Mutation Causes Huntington's Disease, Transforming Understanding of the Disorder Jan. 16, 2025 — Scientists have discovered a surprising mechanism by ...

Huntington's disease is a rare genetic, autosomal dominant, neurodegenerative disease, caused by CAG repeat expansions in the HTT gene, that is polymorphic on the healthy allele and contains more than ...

Image Credit: Shutterstock AI / Shutterstock.com In a recent study published in the journal Nature Metabolism, researchers ...

Instead, the authors propose targeting mechanisms that affect the somatic ... investigated three biological puzzles related to Huntington’s disease: why only specific neurons die, why symptoms ...

New mechanism preventing toxic DNA lesions opens up therapeutic avenues for Huntington's disease Aug 31, 2021 Surprise finding sheds light on what causes Huntington's disease, a devastating fatal ...

According to the University of California San Francisco, Huntington’s disease affects one in every 10,000 to 20,000 people in ...

Despite its increasing prevalence, a painful condition called bladder pain syndrome, or interstitial cystitis, remains ...

Huntington’s disease is a rare ... long and unstable form of the protein that is chopped up by cellular repair mechanisms into smaller, toxic fragments. AMT-130 consists of an adeno-associated ...

Huntington's disease is a rare hereditary neurodegenerative disease affecting over 40,000 patients in the United States and many more worldwide. There are no approved treatments that can reverse ...

ElevateBio is seeking out partnerships for its lead gene therapy after the construct reduced the levels of a toxic protein in mice with Huntington’s disease by more than 80%. The therapy had no ...

Huntington's disease (HD) is a hereditary neurodegenerative disorder ... The abnormal huntingtin is toxic generates death of neurons with though various mechanisms. The part of the gene that is ...