While some people may decry the lack of upsets in the first two rounds of the men’s NCAA Tournament, the result is a Sweet 16 filled with the best teams in the country. All four No. 1 seeds are still alive, and there’s plenty of talent on the rosters who are trying to upset them en route to the Elite Eight.

SportsLine expert Bruce Marshall has revealed his Arizona Wildcats vs. Duke Blue Devils picks for the Sweet 16 of the 2025 NCAA Tournament on Thursday

Of the eight matchups in the NCAA Tournament Sweet 16, the Arizona Wildcats are the biggest underdogs. With Cooper Flagg healthy, Tyrese Proctor shooting the li